Create a future where DNA is no longer destiny. Join Rocket Pharma.

Rocket Pharma is a fully integrated, late-stage biotechnology company advancing gene therapies with curative potential for patients with rare and life-threatening diseases. We are a team of creative, compassionate, and driven individuals united by a profound mission of seeking gene therapy cures. Rocket places tremendous value on our people and fosters a collaborative environment where bold ideas thrive and every team member makes a meaningful impact. Our core values guide everything we do: we trust one another, show generosity toward patients, embrace curiosity, and strive to elevate science. Team members receive a competitive total rewards package, including equity participation, 401(k) matching, and excellent health benefits.

Rocket is seeking a Vice President and Head of Cardiovascular Medicine, to develop transformative cell- and gene-based therapies for rare and life-threatening disorders. The candidate will be responsible for working with the clinical and cross functional teams to define the strategy and execution of innovative clinical studies with gene therapies for cardiomyopathy and related disorders. As a subject matter expert (SME), the candidate will be working on different projects to share their expertise and feedback from a cardiovascular perspective. In addition, the candidate will be the lead study physician/medical director for at least one clinical study. The candidate will serve as member of multi-disciplinary teams governing internal and external clinical collaboration, and work with the team to understand the foundational science from in vitro and in vivo models, translational science and opportunities to extend those findings to clinical trials. The candidate will also serve as a key contributor to the company’s development strategy in close collaboration with the Chief Medical Officer and other senior stakeholders. The candidate will play a pivotal role in the development, conduct and analysis of cell- and gene-therapy clinical programs culminating in health-authority submission and marketing authorization.  

• Reporting to the Chief Medical Officer, the Vice President and Head of Cardiovascular Medicine role will involve intense collaboration with academic investigators/scientific experts to support clinical trials program.
• Along with other responsibilities, the candidate would be responsible end to end, for at least one of the clinical development programs as lead physician, with adherence to GCP guidelines and other relevant health authority regulations.
• Develop and share expertise in the science of various gene therapies in development and the patho-physiologies that occur with genetic variants to permit leading internal and external discussions of strategic approaches to company’s novel therapeutic approaches.
• Develop and advise on clinical protocols for studies as appropriate for ongoing and future development activities.
• Serve as the primary clinical contributor for trial related documentation, protocols and regulatory submissions
• Participate in clinical advisory boards in collaboration with Medical Affairs and cross functional team, steering committees and data safety monitoring boards as required.
• Reviews all medical/scientific publications related to clinical, translational or pre-clinical studies keeping the R&D and BD teams informed, as appropriate.
• Develop imaging and blood biomarkers strategy for cardiac dysfunction and the effects of therapeutic interventions with various agents.
• Provide expert advice on setting up study related databases to capture appropriate cardiac related data points.

• MD or DO with at least 10 years of progressive leadership experience in cardiovascular diseases and clinical research in a clinical/ industry setting is required. Certification or substantial clinical experience in Advanced Heart Failure and Familial/Genetic Cardiomyopathy is highly desirable.
• Deep knowledge of GCPs governing the conduct of clinical trials; working knowledge of the FDA, the EMA and other health authorities Regulations and ICH Guidelines.
• Deep understanding of science and genetics underlying cardiomyopathy and heart failure
• Demonstrated success leading cardiovascular clinical programs, with experience in global trial execution and regulatory submissions strongly preferred
• Proven ability to lead and influence cross-functional teams. Familiarity with innovative imaging technologies in cardiovascular disease research, such as, echocardiography, magnetic resonance imaging, positron emission tomography, and novel or established cell signaling systems.
• Must have ability to work collaboratively as part of a multi-functional drug development team in a dynamic environment.
• Must be self-motivated, highly organized, detail-oriented and able to multi-task, delivering high quality work.
• Excellent oral and written communication skills; excellent interpersonal skills, including the ability to influence and to work effectively cross-culturally and cross-functionally.
• Ability to travel 15-20% of the time is required for investigator meetings/ medical conferences, etc.

The expected salary range for this position is $366,000 to $440,000. 

At Rocket, our compensation philosophy and ranges are built upon data and insights collected from validated world-class providers. We are committed to compensating employees equitably based on several factors, including responsibilities and level of the position, depth and types of the employee’s experience, location of the position and availability of similar talent in a competitive market.

For U.S.-based candidates, this is an at-will position, and Rocket reserves the right to adjust the range at hire or during the year due to market shifts.

In addition to base salary, Rocket offers a competitive total rewards package that may include bonuses (short-term incentives), medical, dental, and vision insurance, life insurance, 401(k) with company match and generous vesting, paid vacation and holidays, global shutdown days between Christmas and New Year’s, and a variety of wellness resources and employee support programs. Also, certain positions are eligible for added forms of compensation, such equity awards (long-term incentives).

A diverse workforce fosters innovation and strengthens Rocket’s business. We ensure equal opportunity without discrimination or harassment in the workplace on the basis of gender, race, color, religion, national origin, age, physical or mental disability, pregnancy, citizenship, status as a protected veteran, marital status, sexual orientation, gender identity and expression, genetic information, or any other characteristic protected by applicable local, state, and federal laws.